Gold-Catalyzed Intramolecular Cyclizations of Cyclopropenes with Propargylic Esters
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چکیده
منابع مشابه
Gold‐Catalyzed Intramolecular Cyclizations of Cyclopropenes with Propargylic Esters
Homogeneous gold catalysts are interesting as they can act as potent carbophilic Lewis acids to activate the π bonds of alkynes, allenes, and alkenes. Many impressive applications for the formation of C-C or C-heteroatom bonds have been found due to the excellent functional group compatibility of these catalysts and the air and moisture tolerance of their reactions. Here, we have developed gold...
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An interesting silver(I)-catalyzed, one-pot intramolecular cyclization of epoxide-propargylic esters is described. A variety of 1,4-oxazine derivatives were obtained through a novel domino sequence, including three-membered ring-opening, 3,3-sigmatropic rearrangement, 6-exo-cycloisomerization and subsequent intramolecular elimination in moderate yields under mild conditions.
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Aldehyde and ketone electrophiles incorporated into the side chains of 2- and 4-alkylpyridines participate in intramolecular aldol-like condensations with pyridine benzylic carbons in the presence of Brønsted acid catalysts. Pyridines featuring β-ketoamide side chains undergo cyclization in the presence of 10 mol% TfOH to afford pyridyl-substituted hydroxy lactams in good yield. These products ...
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An efficient and simple methodology was developed for the synthesis of oxazolidinones, oxazolidinthiones, imidazolidinthiones, and imidazolidinones from the corresponding propargylic starting materials using Pd(OAc)2 and n-Bu4NOAc as catalysts in DCE at room temperature.
متن کاملGold catalysed reactions with cyclopropenes.
Gold(i) catalyses the ring-opening addition of cyclopropenes in a mild and regioselective manner.
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ژورنال
عنوان ژورنال: ChemistryOpen
سال: 2015
ISSN: 2191-1363
DOI: 10.1002/open.201500181